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Introduction

Nearly 7% of the world population is obese1 and about 66% of the adults in the United States are overweight or obese.2 Obesity is associated with a number of adverse medical conditions including increased risk of gallbladder disease, hypertension, type 2 diabetes mellitus, coronary heart disease (CHD), osteoarthritis, cancer death and reduced life expectancy.3–8 Obesity is also associated with adverse social and psychological consequences, including bias, discrimination and decreased quality of life.9,10

More effective treatment strategies are urgently needed for obesity management. The total caloric intake or energy density of one’s diet appears to be associated with obesity11–14 and a diet that induces a negative energy balance continues to be an important part of obesity management. Strategies to achieve the difficult task of eating less than desired include reduction of the energy density of foods by increasing food volume by the addition of fluids,15,16 bulk17–19 or their combination;20 or by increasing satiety by various anorectic drugs or macronutrient combinations of high satiety value.

Satiety is positively associated with the protein, fiber and water content of foods and negatively with fat and palatability ratings.21,22 However, within food groups, there may be as much as a twofold difference in satiety values, suggesting that certain foods promote greater satiety independent of macronutrient content or energy density. An egg is an example of such a food that has a 50% greater satiety index compared to white bread or ready-to-eat breakfast cereal.21 Compared to an isocaloric bagel breakfast of equal weight, an egg breakfast had a greater satiating effect, which translated into a lower caloric intake at lunch.23 The resulting decrease in energy consumption lasted for at least 24 h after the egg breakfast.

This study was undertaken to exploit the short-term satiating benefits of an egg breakfast23 for weight loss in a longer-term trial. The objectives were to determine if the incorporation of an egg breakfast in the diet by overweight or obese subjects would (1) induce reduced energy intake and unintentional weight loss, even when not attempting weight reduction; or (2) enhance weight loss when following a reduced energy diet. We compared the effects of an egg vs isocaloric bagel breakfast of equal weight on weight loss, indices of body size and composition, dietary compliance, food cravings and health-specific quality of life.Materials and methods

The study was approved by the institutional review boards at Pennington Biomedical Research Center and at Saint Louis University. Written informed consent was obtained from the participants. We certify that all applicable institutional and governmental regulations regarding the ethical use of human volunteers were followed during this research.

Participants

Of the 160 participants enrolled, 8 did not complete the trial. The final study sample included 152 participants (131 women and 21 men; mean age 45.0±9.4 years; black participants 47.7% and white participants 52.3%). Demographic characteristics of the participants are provided inTable 1

Communicating with someone who is suffering from depression can be challenging, as it can be difficult to know what to say or how to act. However, it is important to remember that your words and actions can have a significant impact on their mental health and well-being. Here are some tips for communicating with someone who is struggling with depression:

  1. Listen without judgment: Let them express their feelings and emotions without interrupting or dismissing them. Show empathy and understanding, and avoid criticizing or judging their thoughts and actions.

  2. Offer support: Let them know that you are there for them and that they are not alone. Offer to help them in any way that you can, whether it be through listening, providing practical support, or accompanying them to therapy appointments.

  3. Avoid giving advice: While it may be tempting to offer solutions or advice, it is important to recognize that depression is a complex condition that requires professional help. Instead, encourage them to seek support from a healthcare professional.

  4. Be patient: Recovery from depression takes time, and it is important to be patient and understanding. Avoid pressuring them to "snap out of it" or rushing their recovery process.

  5. Practice self-care: Supporting someone with depression can be emotionally taxing, so it is important to take care of your own mental health as well. Set boundaries, seek support from others, and prioritize your own self-care.

  6. Validate their feelings: Depression can be a lonely and isolating experience, so it is important to validate their feelings and let them know that it is okay to feel the way they do. Encourage them to express their emotions and offer reassurance that their feelings are valid and important.

  7. Encourage healthy habits: While it may not cure depression, maintaining healthy habits such as regular exercise, a balanced diet, and adequate sleep can help improve mental health and well-being. Encourage them to engage in these habits and offer to participate with them if possible.

In summary, communicating with someone who is struggling with depression requires patience, empathy, and understanding. By listening without judgment, offering support, avoiding giving advice, being patient, practicing self-care, validating their feelings, and encouraging healthy habits, you can help support them through their recovery process.

Nasal augmentation, also known as rhinoplasty, is a surgical procedure that enhances the shape and size of the nose. It is a popular cosmetic surgery that can improve the appearance of the face and boost self-confidence. Nasal augmentation can also improve the function of the nose by correcting breathing problems caused by structural defects.

There are two types of nasal augmentation procedures: open and closed. Open rhinoplasty involves making an incision in the columella, the tissue that separates the nostrils. This allows the surgeon to lift the skin and tissue of the nose, giving them a better view of the nasal structure. Closed rhinoplasty involves making incisions inside the nostrils, making it a less invasive procedure. Both techniques have their own benefits and risks, and the choice of technique depends on the individual's needs.

The surgeon will typically use either autologous tissue, synthetic material, or a combination of both to augment the nose. Autologous tissue, such as cartilage from the septum or ear, provides a natural-looking and long-lasting result. Synthetic material, such as silicone implants or Gore-Tex, can also provide a satisfactory result but carries a higher risk of complications such as infection and extrusion.

Recovery from nasal augmentation typically takes one to two weeks. Patients may experience bruising, swelling, and discomfort, but these symptoms can be managed with pain medication and ice packs. Patients should avoid strenuous activity and wearing glasses or sunglasses for at least six weeks after surgery. The final result of the surgery may not be fully visible for several months as the swelling subsides and the tissues settle.

In conclusion, nasal augmentation is a safe and effective procedure that can improve the appearance and function of the nose. It is important to choose a skilled and experienced surgeon to ensure the best possible outcome. Patients should also have realistic expectations and understand the risks and benefits of the procedure before undergoing surgery.