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Introduction

Nearly 7% of the world population is obese1 and about 66% of the adults in the United States are overweight or obese.2 Obesity is associated with a number of adverse medical conditions including increased risk of gallbladder disease, hypertension, type 2 diabetes mellitus, coronary heart disease (CHD), osteoarthritis, cancer death and reduced life expectancy.3–8 Obesity is also associated with adverse social and psychological consequences, including bias, discrimination and decreased quality of life.9,10

More effective treatment strategies are urgently needed for obesity management. The total caloric intake or energy density of one’s diet appears to be associated with obesity11–14 and a diet that induces a negative energy balance continues to be an important part of obesity management. Strategies to achieve the difficult task of eating less than desired include reduction of the energy density of foods by increasing food volume by the addition of fluids,15,16 bulk17–19 or their combination;20 or by increasing satiety by various anorectic drugs or macronutrient combinations of high satiety value.

Satiety is positively associated with the protein, fiber and water content of foods and negatively with fat and palatability ratings.21,22 However, within food groups, there may be as much as a twofold difference in satiety values, suggesting that certain foods promote greater satiety independent of macronutrient content or energy density. An egg is an example of such a food that has a 50% greater satiety index compared to white bread or ready-to-eat breakfast cereal.21 Compared to an isocaloric bagel breakfast of equal weight, an egg breakfast had a greater satiating effect, which translated into a lower caloric intake at lunch.23 The resulting decrease in energy consumption lasted for at least 24 h after the egg breakfast.

This study was undertaken to exploit the short-term satiating benefits of an egg breakfast23 for weight loss in a longer-term trial. The objectives were to determine if the incorporation of an egg breakfast in the diet by overweight or obese subjects would (1) induce reduced energy intake and unintentional weight loss, even when not attempting weight reduction; or (2) enhance weight loss when following a reduced energy diet. We compared the effects of an egg vs isocaloric bagel breakfast of equal weight on weight loss, indices of body size and composition, dietary compliance, food cravings and health-specific quality of life.Materials and methods

The study was approved by the institutional review boards at Pennington Biomedical Research Center and at Saint Louis University. Written informed consent was obtained from the participants. We certify that all applicable institutional and governmental regulations regarding the ethical use of human volunteers were followed during this research.

Participants

Of the 160 participants enrolled, 8 did not complete the trial. The final study sample included 152 participants (131 women and 21 men; mean age 45.0±9.4 years; black participants 47.7% and white participants 52.3%). Demographic characteristics of the participants are provided inTable 1

Breast lumps or masses are a common concern among many women. While most breast lumps are non-cancerous and not harmful, it is important to seek medical attention if you notice any changes in your breasts.

Breast lumps can have a variety of causes, including hormonal changes, infections, cysts, fibroadenomas, and breast cancer. In some cases, breast lumps may be caused by breast tissue that is dense or fibrous, making it more difficult to detect changes.

Breast cancer is a serious concern and can be life-threatening if not detected and treated early. Women should perform monthly breast self-exams and seek medical attention if they notice any changes in their breasts such as lumps, swelling, or discharge.

In addition to breast self-exams, regular mammograms and clinical breast exams are important for early detection of breast cancer. Women should talk to their healthcare providers about when to start and how often to have these screenings based on their age and risk factors.

While most breast lumps are not harmful, it is important to seek medical attention if you notice any changes in your breasts. Your healthcare provider can perform a breast exam, order diagnostic tests, and provide guidance on the best course of action based on your individual situation.

Communicating with someone who is suffering from depression can be challenging, as it can be difficult to know what to say or how to act. However, it is important to remember that your words and actions can have a significant impact on their mental health and well-being. Here are some tips for communicating with someone who is struggling with depression:

  1. Listen without judgment: Let them express their feelings and emotions without interrupting or dismissing them. Show empathy and understanding, and avoid criticizing or judging their thoughts and actions.

  2. Offer support: Let them know that you are there for them and that they are not alone. Offer to help them in any way that you can, whether it be through listening, providing practical support, or accompanying them to therapy appointments.

  3. Avoid giving advice: While it may be tempting to offer solutions or advice, it is important to recognize that depression is a complex condition that requires professional help. Instead, encourage them to seek support from a healthcare professional.

  4. Be patient: Recovery from depression takes time, and it is important to be patient and understanding. Avoid pressuring them to "snap out of it" or rushing their recovery process.

  5. Practice self-care: Supporting someone with depression can be emotionally taxing, so it is important to take care of your own mental health as well. Set boundaries, seek support from others, and prioritize your own self-care.

  6. Validate their feelings: Depression can be a lonely and isolating experience, so it is important to validate their feelings and let them know that it is okay to feel the way they do. Encourage them to express their emotions and offer reassurance that their feelings are valid and important.

  7. Encourage healthy habits: While it may not cure depression, maintaining healthy habits such as regular exercise, a balanced diet, and adequate sleep can help improve mental health and well-being. Encourage them to engage in these habits and offer to participate with them if possible.

In summary, communicating with someone who is struggling with depression requires patience, empathy, and understanding. By listening without judgment, offering support, avoiding giving advice, being patient, practicing self-care, validating their feelings, and encouraging healthy habits, you can help support them through their recovery process.